Laboratory and Field Research in Protist Genomics, Plant Molecular
Systematics (Delwiche) Lab

We seek highly motivated undergraduates to assist in laboratory operations
and to carry out directed research projects. Our laboratory performs
genome analyses to address fundamental questions in evolution and ecology,
particularly concerning the evolutionary origin of organelles, the
evolution of organellar genomes, and the early diversification of plants.
Most of our work consists of studies of biological diversity in eukaryotic
microorganisms including dinoflagellates and green algae. The lab is
fundamentally a molecular biology lab, but much of our work is genomic,
and there are opportunities for students with interests in mathematics,
computer science, or systems biology as well as in organismal and
molecular biology. Undergraduates working in the lab function as full
laboratory members, and have opportunities for laboratory, field, and
computational research as appropriate to the interests and skills of the
student. 

Possible projects for semi-independent undergraduate research might
include: 1) participation in development of a new transformation system
(i.e., creating transgenic algae), which will be used for study of plant
development 2) competition experiments in laboratory microcosms, which
will help understand community growth dynamics and responses to
environmental change in freshwater systems; 3) genome size estimation via
flow cytometry and microscopy, with implications for genome evolution and
the c-value paradox; and 4) bioinformatic studies of large and complex
transcriptome databases, in part to examine why some single-celled
organisms have genomes that are over a hundred-fold larger than the human
genome.

Initially, the work will consist primarily of general laboratory
assistance and supervised work. Methods in active use in the lab include
Sanger and "next-gen" Illumina DNA/RNA sequencing techniques, sterile
culture, electrophoresis, centrifugation, microscopy, flow cytometry, and
bioinformatics. With added experience, the student will be given increased
independence, with a ultimate goal of academic publication. Participation
in a Departmental honors program or HHMI-funded independent research is
encouraged. Related experience, such as course-work in microbiology or
computer programming is helpful.

To apply, send a Curriculum Vitae (CV) or resume; a testudo print-out of
your transcripts; information about your time commitments and availability
during Summer, Fall semester, and later; and names of three people
familiar with your work who could serve as references to:
[log in to unmask] There is no formal closing date, but applications
received before April 15 will be assured full consideration.