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CAST10  September 2015

CAST10 September 2015

Subject:

Sr. Engineer Position @ Amgen

From:

Cenk Undey <[log in to unmask]>

Reply-To:

Cenk Undey <[log in to unmask]>

Date:

Fri, 18 Sep 2015 14:09:56 -0400

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (90 lines)

We have an exciting opening in our group at Amgen in Digital Integration 
and Predictive Technologies (DIPT) group in the area of Process 
Analytics. Job location is Cambridge, MA. 

For those who are interested please apply (Req #: 34229BR) using the 
following link or send me an e-mail at [log in to unmask]


http://careers.amgen.com/en/jobs/descriptions/sr-engineer-digital-
integration-and-predictive-technologies-cambridge-job-5823853


Job Summary:
Amgen’s Digital Integration and Predictive Technologies orginization is 
a global process development function that develops and deploys state of 
the art advanced computational technologies in: 1) data capture, 
integration and management, 2) empirical and first principles modeling 
towards improved process understanding and robustness, and 3) 
monitoring, prediction and optimization of manufacturing. We are seeking 
a Senior Engineer to provide hands-on technical support, analyses, and 
assessments for a broad base of clients globally by leveraging expertise 
in process analytics, computational and multivariate modeling for 
production of bio-therapeutics. The Senior Engineer will address a wide 
variety of challenging problems across many organizations including: 
drug substance, drug product and drug delivery devices. Responsibilities 
will include designing and running bench-scale experiments for model-
based control studies, preparation of internally reviewed technical 
reports as well as participation in and presentation of results at 
department and project meetings. Use of developed models and their 
underlying technical basis will be deployed and taught to the broader 
engineering and scientist community responsible for delivering processes 
to operations 


Basic Qualifications 

Doctorate Degree OR Master's Degree & 3 years of Engineering experience 
OR Bachelor's Degree & 5 years of Engineering experience OR Associate's 
degree & 10 years of Engineering experience OR High school diploma/GED & 
12 years of Engineering experience



Preferred Qualifications 


Ph.D. with experience noted in the basic qualifications above.

5+ years relevant work experience in bio/pharmaceutical applications.


Experience in process development and/or Computational Modeling and 
Control techniques 

Experience with biopharmaceuticals processes, related unit operations.

Solid understanding of biochemical engineering, metabolic flux models 
and closed-loop control.

Hands-on bench or pilot-lab experience to work with experimentalists to 
generate data for model building and validation

Excellent programming skills in any of the following: C++, Perl, Java, 
C# , Matlab, Python, R

Basic understanding of laboratory automation and information systems 
such as Delta V, OPC and PI.

Knowledge of current state of the art technologies and emerging 
scientific and regulatory directions for process control towards 
minimizing and controlling process variability as well as new 
technologies to improve control, information and knowledge management in 
process lifecycle.

Strong interdisciplinary project management skills.

Ability to independently uncover and resolve issues associated with the 
development and implementation of scientific and engineering projects.

Should be recognized in the scientific and engineering community through 
a sustained record of publications and/or patents.

Understanding of bulk protein process and formulation/finish unit 
operations including analytical methods and process controls. 


Amgen is an Equal Opportunity employer and will consider all qualified 
applicants for employment without regard to race, color, religion, sex, 
sexual orientation, gender identity, national origin, protected veteran 
status, or disability status.

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