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March 2017

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Subject:
From:
"Shruti V. Kabadi, Ph.D." <[log in to unmask]>
Reply To:
Daily eNews for CMNS Students <[log in to unmask]>
Date:
Mon, 20 Mar 2017 13:29:02 -0500
Content-Type:
text/plain
Parts/Attachments:
text/plain (48 lines)
Subject: Summer Internship Opportunity at FDA

Description:
Project: Consideration of inhalation studies for risk assessment of oral
exposure of metals

Project Summary:
The objective of this project is to evaluate the relevance and significance
of data from inhalation studies for risk assessment of oral exposure to
metals such as cobalt, nickel and cadmium. This project will involve
collection and review of published pharmacokinetic data from the scientific
literature for assessment of internal exposure of inhalation versus oral
exposure to metals. Furthermore, the collected data will be utilized for
building, validating and applying a physiologically-based pharmacokinetic
(PBPK) model to perform route to route extrapolation.

Skills:
The selected candidate will receive training for developing the following
skills:
• Experience in collection and review of pharmacokinetic data followed by
utilization of the data for estimation of pharmacokinetic parameters.
• Understanding of basic pharmacokinetic modeling with hands-on exercises
using commonly-available pharmacokinetic softwares.
• Knowledge of the use of pharmacokinetic analysis for evaluation of
toxicological data and performing safety assessment of test substances.
• Opportunities of presenting the analyzed data and reporting research
findings

Requirements:
The candidates must be currently enrolled in a graduate or undergraduate
program majoring in a discipline of science such as biology and chemistry.
Coursework in pharmacology, toxicology, pharmacokinetics, physiology or
related discipline is preferred but not required.

The position will be confirmed upon management review.
Interested candidates should send their resume to Dr. Shruti Kabadi at
[log in to unmask] no later than March 27, 2017. If you have any
questions, please feel free to contact Dr. Kabadi directly.

Duration: 3 months (Stipend provided: $800 per week)
Appointment Period: June 1, 2017 to August 31, 2017
Application Deadline: March 27, 2017

Event Location: FDA/CFSAN/OFAS, 5001 Campus Drive, College Park, MD 20740
Contact Person: Shruti V. Kabadi, Ph.D.
Contact Email: [log in to unmask]
Contact Phone Number: (240) 402-6593

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