We have an exciting opening in our group at Amgen in Digital Integration
and Predictive Technologies (DIPT) group in the area of Process
Analytics. Job location is Cambridge, MA.
For those who are interested please apply (Req #: 34229BR) using the
following link or send me an e-mail at [log in to unmask]
Amgen’s Digital Integration and Predictive Technologies orginization is
a global process development function that develops and deploys state of
the art advanced computational technologies in: 1) data capture,
integration and management, 2) empirical and first principles modeling
towards improved process understanding and robustness, and 3)
monitoring, prediction and optimization of manufacturing. We are seeking
a Senior Engineer to provide hands-on technical support, analyses, and
assessments for a broad base of clients globally by leveraging expertise
in process analytics, computational and multivariate modeling for
production of bio-therapeutics. The Senior Engineer will address a wide
variety of challenging problems across many organizations including:
drug substance, drug product and drug delivery devices. Responsibilities
will include designing and running bench-scale experiments for model-
based control studies, preparation of internally reviewed technical
reports as well as participation in and presentation of results at
department and project meetings. Use of developed models and their
underlying technical basis will be deployed and taught to the broader
engineering and scientist community responsible for delivering processes
Doctorate Degree OR Master's Degree & 3 years of Engineering experience
OR Bachelor's Degree & 5 years of Engineering experience OR Associate's
degree & 10 years of Engineering experience OR High school diploma/GED &
12 years of Engineering experience
Ph.D. with experience noted in the basic qualifications above.
5+ years relevant work experience in bio/pharmaceutical applications.
Experience in process development and/or Computational Modeling and
Experience with biopharmaceuticals processes, related unit operations.
Solid understanding of biochemical engineering, metabolic flux models
and closed-loop control.
Hands-on bench or pilot-lab experience to work with experimentalists to
generate data for model building and validation
Excellent programming skills in any of the following: C++, Perl, Java,
C# , Matlab, Python, R
Basic understanding of laboratory automation and information systems
such as Delta V, OPC and PI.
Knowledge of current state of the art technologies and emerging
scientific and regulatory directions for process control towards
minimizing and controlling process variability as well as new
technologies to improve control, information and knowledge management in
Strong interdisciplinary project management skills.
Ability to independently uncover and resolve issues associated with the
development and implementation of scientific and engineering projects.
Should be recognized in the scientific and engineering community through
a sustained record of publications and/or patents.
Understanding of bulk protein process and formulation/finish unit
operations including analytical methods and process controls.
Amgen is an Equal Opportunity employer and will consider all qualified
applicants for employment without regard to race, color, religion, sex,
sexual orientation, gender identity, national origin, protected veteran
status, or disability status.