Subject: Biologist/Laboratory Manager

Description:
Biologist/Laboratory Manager

Position is located in the Molecular Neuropharmacology Section within the
Intramural Research Program, NINDS, NIH. The Section conducts molecular and
cell biological studies of neurotransmitter receptor systems in order to
elucidate their structure, function and regulatory mechanisms. A specific
focus of the laboratory is on the discovery and development of drugs
targeting dopamine receptors in relations to the treatment of
neuropsychiatric disorders. The incumbent will serve as a research biologist
in this field of study and will be responsible for managing a variety of
laboratory operations.

Duties and Responsibilities:

Plans and executes experiments involving the pharmacological characterization
of neurotransmitter receptors, including G protein-coupled receptors (GPCRs)
generally, dopamine receptors specifically. Performs a variety of molecular
biological, biochemical, and pharmacological techniques; including both
membrane and live cell-based signaling assays – knowledge of cell culture
is particularly helpful. Performs other molecular, cell biological, or
biochemical techniques related to these specific lines of research. The
incumbent will also perform specific laboratory management procedures and
duties as delegated by the Section Chief.

Develops working details of assignments; prepares materials necessary for
experiments; determines when modifications and adjustments are necessary,
records details of experimental procedures, results and protocols. Analyzes,
summarizes and interprets data obtained from research studies; evaluates for
completeness and validity; draws conclusions about the results as related to
the ability of the experiments to answer the questions posed. Presents
results and conclusions in written, tabular and graphic form; prepares
accumulated data and conclusions for publication in professional journals.

Trains new laboratory personnel in experimental procedures and protocols.
Assists senior laboratory staff in specific experiments and projects.

Manages transgenic mouse colony. Oversees breeding of animals and genotypes
animals as required.

Coordinates general laboratory maintenance including equipment upkeep,
structural modifications, procurement and inventory needs, and other
laboratory operations designated by the Chief.

Requirements:

• Minimum requirements include a Bachelor’s degree in Biology, or a
related discipline, and two years of relevant experience. Master’s degree
is preferred.
• Strong communications skills, both oral and written.
• Excellent analytical, organizational and time management skills.
• Must not be allergic to mice.

Salary is dependent on level of education and years of experience.

To apply, please send CV/resume and a statement of background and experience
to:

David R. Sibley, Ph.D.
Chief, Molecular Neuropharmacology Section
National Institute of Neurological Disorders & Stroke/NIH
Email: [log in to unmask]
http://intra.ninds.nih.gov/Lab.asp?Org_ID=67


Event Location: NIH
Contact Person: Dr. David Sibley
Contact Email: [log in to unmask]
Contact Phone Number: 301-496-9316
Website URL: http://http://intra.ninds.nih.gov/Lab.asp?Org_ID=67