FOCAPO 2008 (Foundations of Computer-Aided Process Operations) is the 5th international conference offered by the CACHE organization to review the advances and address the challenges of process operations. It will take place at the Royal Sonesta in Cambridge, MA between June 29th and July 2nd. There are a number of exciting invited speakers for the sessions to be held Monday to Wednesday, in addition to William Pulleybank from IBM being the Keynote speaker on Sunday evening. The sessions cover: Integration of Control, Scheduling, and Planning; Enterprise-Wide Optimization; Modeling, Optimization, and Information Technologies; Forecasting, Finance, and Risk Management; Sustainable Resource Systems; and Emerging Technologies. A major part of the conference is the session of Contributed Papers. In the context of the theme of the conference "Multi-Scale Integration of R&D, Manufacturing, and Optimization for Enterprise-Wide Operations" we are seeking papers that cover the traditional process operations areas in addition to areas that may not have been focused on at previous FOCAPO conferences.These non-traditional areas might include energy, multiscale modeling, systems biology, nano-applications, etc. Abstracts of no longer than 500 words are being accepted until October 1, 2007. For more details on the conference and how to submit a contributed paper abstract see FOCAPO.org.