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PhD Positions: Mathematical Modeling and Analysis Applications are invited for two PhD positions in the Systems Biology Group of the Hamilton Institute at the National University of Ireland, Maynooth. The vacancies are in the area of mathematical modeling and model analysis. The advertised positions are part of a Higher Education Authority investment for a National Biophotonics Imaging Platform (NBIP) for Ireland. NBIP is the largest European network in Biological Imaging and its mission is to provide an integrated national infrastructure in research, education, technology development and industry collaboration for Biophotonics and Imaging. The Systems Biology Group at the Hamilton Institute will coordinate the Image to Mathematical Model Transition (IMMT) facility of the NBIP. The vacancies will be focussed on (but not limited to) the following application areas: (1) Apoptotic signalling through Bcl-2 family members: From advances in single cell imaging to new systems approaches. This research will deliver new insights into the temporal and spatial dynamics of Bcl-2 family protein activation and interaction at the single cell and single molecule level. (2) Visualization and image analysis of neural injury, plasticity and repair. This research will investigate which changes contribute to long-term plasticity and repair during chronic pain and neurodegeneration. The candidate should hold a BSc. in Engineering/Mathematics or a related field, and have a sound scientific record in the area of mathematical modeling and model analysis. Good communication, interpersonal and presentation skills are required. Some background in biology or biochemistry is highly desirable. Proficiency in both written and spoken English is required. The positions are available for a four-year period with an annual stipend of 19,000 Euros. For further information on the Hamilton Institute, please refer to: www.hamilton.ie and www.systemsbiology.ie. Additional information about the posts can be obtained from Dimitris Kalamatianos ([log in to unmask]). To apply, candidates should submit a detailed CV, including a list of publications (if available), motivation letter, scientific interests, as well as the names and addresses of two referees for letters of recommendation to: [log in to unmask]