Dear Colleagues,

We have scheduled a number of two-day courses on batch process modeling, cost analysis, production scheduling, throughput analysis, cycle time reduction, debottlenecking, and waste minimization at various Universities around the globe. The courses are intended for scientists and engineers in the Pharmaceutical, Biotech, Fine Chemical, Food, and Consumer Product industries that are interested in:

* Modeling and Optimization of Batch and Continuous Processes
* Cost of Goods Analysis & Project Economic Evaluation
* Cycle Time Reduction and Throughput Analysis
* Production Scheduling and Debottlenecking
* Variability Reduction
* Pollution Prevention and Control

The courses include theory on the above subjects and hands-on sessions with process simulation and scheduling tools that facilitate the above tasks. The courses are taught by experts from industry and academia.

Instructors at colleges and universities that teach Biochemical Engineering, Pharmaceutical Engineering, Process and Plant Design, Food Engineering, and related courses are welcome to attend.

UPCOMING COURSES - DATES AND VENUES

Belgium, Antwerpen, May 13-14, 2008
Karel de Grote - Hogeschool
Chemical Department
Salesianenlaan 30
B-2660 Hoboken, Belgium

USA, Raleigh, NC, May 15-16, 2008
North Carolina State University
Biomanufacturing Training & Education Center (BTEC)
Raleigh, NC 27695-7905

USA, Boston, MA, June 9-10, 2008
Tufts University
Chemical and Biological Engineering
4 Colby Street
Medford, MA 02155

USA, West Lafayette, IN, October 13-14, 2008
Purdue University
Agricultural and Bio Engineering
225 S University Street
West Lafayette, IN 47907-1146

China, Dalian, October 18-19, 2008
Dalian University of Technology
Dept of Bioscience and Bioengineering
158 Zhongshan Rd.
Dalian, 116012, China
Combine it with IBS2008

Netherlands, Delft, End of October, 2008
TU Delft
Department of Biotechnology
Julianalaan 67
2628 BC Delft, The Netherlands

You may register for a course by responding to this message.

SIMILAR COURSES WILL BE OFFERED IN OTHER PARTS OF THE WORLD. For additional locations and dates, please point your browser to: http://www.intelligen.com/training.shtml

PLEASE FORWARD THIS MESSAGE TO ANY OF YOUR COLLEAGUES THAT MAY HAVE AN INTEREST IN THE SUBJECT.

If you have any questions, please do not hesitate to contact me.

Best Regards,

Demetri Petrides, Ph.D.
President
INTELLIGEN, INC.
2326 Morse Avenue
Scotch Plains, NJ 07076
Tel: (908) 654-0088
Mobile: (908) 397-7507
Fax: (908) 654-3866
Email: [log in to unmask]
http://www.intelligen.com

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AGENDA FOR THE TWO-DAY WORKSHOPS
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FIRST DAY
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MORNING SESSION
9:00 - 9:45 AM - Interface fundamentals
9:45 - 10:30 AM - Flowsheet development and initialization
10:30 - 10:45 AM - Coffee Break
10:45 - 12:00 Noon - Material Balances & Equipment Sizing

12:00 - 1:00 PM - Lunch Break

AFTERNOON SESSION
1:00 - 2:00 PM - Process Scheduling & Resource Tracking
2:00 - 3:00 PM - Project Economic Evaluation
3:00 - 3:30 PM - Coffee Break
3:30 - 5:00 PM - Overview of Unit Operation Models

SECOND DAY
====================
MORNING SESSION
9:00 - 10:30 AM - Throughput analysis and Debottlenecking
10:30 - 11:00 AM - Coffee Break
11:00 - 12:00 Noon - Cycle Time Reduction

12:00 - 1:00 PM - Lunch Break

AFTERNOON SESSION
1:00 - 2:00 PM - Variability Reduction
2:00 - 3:00 PM - Scheduling of Multi-Product Facilities
3:00 - 3:30 PM - Coffee Break
3:30 - 5:00 PM - Q&A and Miscellaneous Topics

The contents of the courses are often adjusted to meet the specific needs of the attendees.

IF YOU CANNOT ATTEND OUR WORKSHOP BUT ARE INTERESTED IN THE ABOVE SUBJECTS, YOU MAY WANT TO VISIT OUR WEBSITE (http://www.intelligen.com) AND DOWNLOAD THE FOLLOWING:

1) The functional Evaluation version of SuperPro Designer that enables you to test everything and save small flowsheets.

2) A book chapter on BIOPROCESS DESIGN AND ECONOMICS. This is useful material for professionals in biotechnology and biochemical engineering professors. It provides valuable introductory material on bioprocess design and three thorough case studies on: i) Citric Acid, ii) Biosynthetic Human Insulin (Eli Lilly's process), and iii) Therapeutic Monoclonal Antibodies. The complete book can be purchased from Oxford University Press (http://www.oup-usa.org/isbn/0195123409.html).

3) (NEW) A detailed SuperPro example on Monoclonal Antibody Production. Topics covered in the example include:

Efficient modeling of the main manufacturing process.
Modeling of buffer preparation and holding activities.
Advanced modeling of chromatography steps.
Representation of transfer panels and delivery lines.
Cycle time reduction with staggered equipment (i.e., pools of equipment operating out of phase).
Correct modeling of consumables.
Cost of goods analysis.

4) (NEW) A paper on The Role of Simulation and Scheduling Tools in the Development and Manufacture of Pharmaceutical Products. This article was published in the November, 2007, issue of Information Technology Innovations, an addendum to Pharmaceutical Technology.

5) (NEW) A paper on Risk Assessment, Variability Analysis, and Monte Carlo Simulation.

6) (NEW) A paper on Corn to Ethanol Conversion written by scientists at a Research Center of USDA. The process was modeled and evaluated using SuperPro Designer. The SuperPro file also can be downloaded from our website.

7) (NEW) A paper on Bio-diesel Production written by scientists at a Research Center of USDA. The process was modeled and evaluated using SuperPro Designer. The SuperPro file also can be downloaded from our website.

8) A paper on THROUGHPUT ANALYSIS AND DEBOTTLENECKING OF BIOMANUFACTURING FACILITIES. This article was published in the August, 2002, issue of BioPharm. It focuses on debottlenecking and cycle time reduction of monoclonal antibody production processes.

9) A Powerpoint file on THROUGHPUT ANALYSIS, DEBOTTLENECKING, AND ECONOMIC EVALUATION OF INTEGRATED BIOCHEMICAL PROCESSES. The presentation includes introductory material on process modeling, theory on throughput analysis and debottlenecking, an example based on a biopharmaceutical process, and cost analysis results. The complete text of the presentation can be found in the "Notes" page of the slides. This is valuable material for professionals in the biopharmaceutical industry that deal with process development and product commercialization.

10) A Powerpoint file on THROUGHPUT ANALYSIS AND TECHNOLOGY TRANSFER of a synthetic pharmaceutical process. The complete text of the presentation can be found in the "Notes" page of the slides. This is valuable material for professionals in the pharmaceutical and specialty chemical industries that deal with process development and manufacturing.

11) A paper and a Powerpoint file on "EVALUATION OF WATER RECYCLING OPTIONS AT A SEMICONDUCTOR FABRICATION PLANT USING PROCESS SIMULATION". The principles and ideas can be readily extended to any other industrial facility that utilizes large amounts of water and has a need for recycling.

12) A Powerpoint file on VISUALIZATION AND DEBOTTLENECKING OF PRODUCT FORMULATION AND PACKAGING PROCESSES. It is applicable to professionals in the food, consumer product, pharmaceutical, beverage, and related industries. Essentially, whenever there is a combination of batch and semi-continuous processing steps that share equipment across product lines, SuperPro can be used to reduce cycle times and increase plant throughput.

13) A paper on THE ROLE OF PROCESS SIMULATION IN PHARMACEUTICAL PROCESS DEVELOPMENT AND PRODUCT COMMERCIALIZATION. This paper appeared in the Jan/Feb, 2002, issue of Pharmaceutical Engineering (the main publication of ISPE). It provides info on the role of batch process simulators in facilitating development and commercialization of bulk pharmaceuticals.

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Textbook on "Bioseparations Science and Engineering"
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Many of you downloaded in the past my book chapter on Bioprocess Design and Economics. You may now purchase the entire book from Oxford University Press (just point your browser to: http://www.oup-usa.org/isbn/0195123409.html or go to amazon.com and search based on the title). The original chapter on Design and Economics can still be downloaded (free of charge) from our website (http://www.intelligen.com/literature.shtml).

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New book on "Development of Sustainable Bioprocesses: Modeling and Assessment"
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by Elmar Heinzle, Arno P. Biwer, and Charles Cooney, John Wiley & Sons, 2006. This book includes 11 bioprocesses modeled and analyzed with SuperPro Designer. You may purchase the book from the published http://www.wiley.com/WileyCDA/WileyTitle/productCd-0470015594.html?cid=RSS_WILEY2_LIFEMED or at a discount from Amazon.com.