Dear
Colleagues,
We have
scheduled a number of two-day courses on batch process modeling, cost of goods analysis, production
scheduling, capacity analysis, cycle time reduction, debottlenecking, and waste
minimization at various Universities around the globe. The
courses are intended for scientists and engineers in the Pharmaceutical, Biotech,
Fine Chemical, Bio-fuel, Food, and Consumer Product industries
that are interested in:
* Modeling and
Optimization of Batch and Continuous Processes
* Cost of Goods Analysis
* Cycle Time Reduction
and Debottlenecking
* Production Planning
and Scheduling
* Capacity Analysis
* Variability Reduction
* Lean Manufacturing
* Pollution Prevention
and Control
The courses include theory on the above subjects and hands-on sessions with
process simulation and scheduling tools that facilitate the above tasks.
The courses are taught by experts from industry and academia.
Instructors at colleges and universities that teach Biochemical Engineering,
Pharmaceutical Engineering, Process and Plant Design, Food Engineering, and
related courses are welcome to attend.
UPCOMING
COURSES - DATES AND VENUES
Belgium, Antwerpen, April 23-25, 2009
Karel de Grote - Hogeschool
Chemical Department
Salesianenlaan 30
B-2660 Hoboken, Antwerpen, Belgium
USA,
Raleigh, NC, May 14-15, 2009
North Carolina State University
Biomanufacturing Training & Education Center (BTEC)
Raleigh, NC 27695-7905
USA, Boston, MA, June 8-9, 2009
Tufts University
Chemical and Biological Engineering
4 Colby Street
Medford, MA 02155
USA,
Boulder, CO, July 9-10, 2009
University of Colorado
Chemical and Biological Engineering
1111 Engineering Drive
Boulder, CO 80309-0424
USA, West
Lafayette, IN, October 12-13, 2009
Purdue University
Agricultural and Bio Engineering
225 S University Street
West Lafayette, IN 47907-1146
Netherlands,
Delft, end of October, 2009
TU
Delft
Department of Biotechnology
Julianalaan 67
2628 BC Delft, The Netherlands
Puerto
Rico, San Juan, end of February, 2010
Polytechnic
University of Puerto Rico
Chemical Engineering Department
377 Ave. Ponce de Leon
Hato Rey, PR 00919
www.pupr.edu
You may
register for a course by responding to this message.
SIMILAR COURSES WILL BE OFFERED IN OTHER PARTS OF THE WORLD. For additional
venues and dates, please point your browser to: http://www.intelligen.com/training.shtml
PLEASE FORWARD THIS
MESSAGE TO ANY OF YOUR COLLEAGUES THAT MAY HAVE AN INTEREST IN THE SUBJECT.
If you have any questions, please do not hesitate to contact me.
Best Regards,
Demetri Petrides, Ph.D.
President
INTELLIGEN, INC.
2326 Morse Avenue
Scotch Plains, NJ 07076
Tel: (908) 654-0088
Mobile: (908) 397-7507
Fax: (908) 654-3866
Email: [log in to unmask]
http://www.intelligen.com
=====================================
AGENDA FOR THE TWO-DAY WORKSHOPS
=====================================
FIRST DAY
==================
MORNING SESSION
9:00 - 9:45 AM - Interface fundamentals
9:45 - 10:30 AM - Flowsheet development and initialization
10:30 - 10:45 AM - Coffee Break
10:45 - 12:00 Noon - Material Balances & Equipment Sizing
12:00 - 1:00 PM - Lunch Break
AFTERNOON SESSION
1:00 - 2:00 PM - Process Scheduling & Resource Tracking
2:00 - 3:00 PM - Project Economic Evaluation
3:00 - 3:30 PM - Coffee Break
3:30 - 5:00 PM - Overview of Unit Operation Models
SECOND DAY
====================
MORNING SESSION
9:00 - 10:30 AM - Throughput analysis and Debottlenecking
10:30 - 11:00 AM - Coffee Break
11:00 - 12:00 Noon - Cycle Time Reduction
12:00 - 1:00 PM - Lunch Break
AFTERNOON SESSION
1:00 - 2:00 PM - Variability Reduction
2:00 - 3:00 PM - VOC Emission & Pollution Control
3:00 - 3:30 PM - Coffee Break
3:30 - 5:00 PM - Q&A and Miscellaneous Topics
The contents of the courses are often adjusted to meet the specific needs of
the attendees.
IF YOU
CANNOT ATTEND OUR WORKSHOP BUT ARE INTERESTED IN THE ABOVE SUBJECTS, YOU MAY
WANT TO VISIT OUR WEBSITE (http://www.intelligen.com) AND DOWNLOAD THE
FOLLOWING:
1) The functional Evaluation versions of SuperPro Designer and SchedulePro.
2) A book chapter on Bioprocess Design and
Economics. This is useful material for professionals in
biotechnology and biochemical engineering professors. It provides valuable
introductory material on bioprocess design and three thorough case studies on:
i) Citric Acid, ii) Biosynthetic Human Insulin (Eli Lilly's process), and iii)
Therapeutic Monoclonal Antibodies. The complete book can be purchased from
Oxford University Press (http://www.oup-usa.org/isbn/0195123409.html).
3) A paper
on the Systematic Evaluation of Single-Use
Systems Using Process Simulation Tools. A version of this article
appeared in the November, 2008, Guide to Disposables, a supplement to
BioPharm International. This article evaluates the impact of single-use systems
(disposables) on production cost, demand for cleaning materials, demand for
consumables, and production cycle time. The analysis is done for a typical cell
culture facility producing therapeutic monoclonal antibodies. The SuperPro
models used for this example also can be downloaded from the same page of our
website.
4) A paper
on The Role of Simulation and Scheduling Tools in
the Development and Manufacture of Pharmaceutical Products. This
article appeared in the July 2007 issue of Chemical Engineering Research and
Design (an IChemE publication). It provides information on the benefits from
the use of process simulation and finite capacity scheduling tools in the
development and manufacture of pharmaceutical products. An illustrative example
focusing on Tablet Manufacturing is included. Topics covered in the article
include: Materials Balances, Cost of Goods Analysis, Cycle Time Analysis and Reduction,
Uncertainty and Variability Analysis, Production Planning and Scheduling.
5) A paper
on Risk Assessment, Variability Analysis, and
Monte Carlo Simulation.
6) A paper on Corn to Ethanol Conversion
written by scientists at a Research Center of USDA. The process was modeled and
evaluated using SuperPro Designer. The SuperPro file also can be downloaded
from our website.
7) A paper on Bio-diesel Production
written by scientists at a Research Center of USDA. The process was modeled and
evaluated using SuperPro Designer. The SuperPro file also can be downloaded
from our website.
8) A paper on THROUGHPUT ANALYSIS AND DEBOTTLENECKING OF BIOMANUFACTURING
FACILITIES. This article was published in the August, 2002, issue of BioPharm.
It focuses on debottlenecking and cycle time reduction of monoclonal antibody
production processes.
9) A Powerpoint file on THROUGHPUT ANALYSIS, DEBOTTLENECKING, AND ECONOMIC
EVALUATION OF INTEGRATED BIOCHEMICAL PROCESSES. The presentation includes
introductory material on process modeling, theory on throughput analysis and
debottlenecking, an example based on a biopharmaceutical process, and cost
analysis results. The complete text of the presentation can be found in the
"Notes" page of the slides. This is valuable material for
professionals in the biopharmaceutical industry that deal with process
development and product commercialization.
10) A Powerpoint file on THROUGHPUT ANALYSIS AND TECHNOLOGY TRANSFER of a
synthetic pharmaceutical process. The complete text of the presentation can be
found in the "Notes" page of the slides. This is valuable material
for professionals in the pharmaceutical and specialty chemical industries that
deal with process development and manufacturing.
11) A paper and a Powerpoint file on "EVALUATION OF WATER RECYCLING
OPTIONS AT A SEMICONDUCTOR FABRICATION PLANT USING PROCESS SIMULATION".
The principles and ideas can be readily extended to any other industrial
facility that utilizes large amounts of water and has a need for recycling.
12) A Powerpoint file on VISUALIZATION AND DEBOTTLENECKING OF PRODUCT
FORMULATION AND PACKAGING PROCESSES. It is applicable to professionals in the
food, consumer product, pharmaceutical, beverage, and related industries.
Essentially, whenever there is a combination of batch and semi-continuous
processing steps that share equipment across product lines, SuperPro can be
used to reduce cycle times and increase plant throughput.
13) A paper on THE ROLE OF PROCESS SIMULATION IN PHARMACEUTICAL PROCESS
DEVELOPMENT AND PRODUCT COMMERCIALIZATION. This paper appeared in the Jan/Feb,
2002, issue of Pharmaceutical Engineering (the main publication of ISPE). It
provides info on the role of batch process simulators in facilitating
development and commercialization of bulk pharmaceuticals.
RECOMMENDED
TEXTBOOKS
Bioseparations
Science and Engineering
Many of you downloaded in the past my book chapter on Bioprocess Design and
Economics. You may now purchase the entire book from Oxford University Press
(just point your browser to: http://www.oup-usa.org/isbn/0195123409.html or go to amazon.com
and search based on the title). The original chapter on Design and Economics
can still be downloaded (free of charge) from our website (http://www.intelligen.com/literature.shtml).
Development of Sustainable Bioprocesses: Modeling
and Assessment
by Elmar Heinzle, Arno P. Biwer, and Charles Cooney, John Wiley & Sons,
2006. This book includes 11 bioprocesses modeled and analyzed with SuperPro
Designer. The SuperPro files of the 11 bioprocesses are available on a CD that
is shipped with the book. You may purchase the book from the publisher http://www.wiley.com/WileyCDA/WileyTitle/productCd-0470015594.html?cid=RSS_WILEY2_LIFEMED
or at a discount from Amazon.com.