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RESEARCH SEMINAR

Searching for Hidden Treasure in Nature: 
Application of Basic Scientific Techniques in the Design of Two Anti-AIDS Drugs

Who: Dr. Eddy Arnold, Board of Governors Professor of
Chemistry and Chemical Biology, Rutgers University

When:  Friday, February 10 at 12 PM

Where: Bioscience Research Building, Room 1103

Professor Eddy Arnold will describe how a 
multidisciplinary
team of investigators used structure-based approaches to design two 
anti-AIDS
drugs.  Both drugs are remarkably effective against drug-resistant
variants of HIV and work by targeting the HIV reverse transcriptase
enzyme.  Dr. Arnold led a team that used X-ray crystallography to 
visualize
how candidate drug molecules block the action of reverse transcriptase. 
Dr. Arnold’s daughter Lizzie Arnold is a senior biology and psychology 
major at
the University of Maryland.