Hi CAST10 members, Please circulate this ad to anyone who might be interested in. This is a great opportunity to implement your training on PCA/PLS in PAT (Process Analytical Technology) area of biotherapeutics development and production. Please make sure to contact either the FDA staff (not me) or refer to the attachment. Cheers, Seongkyu Yoon ---- University of Massachusetts Lowell, Chemical Engineering and BMEBT Program Systems Biology Research Group Biopharmaceutical Consortium (www.uml.edu/bpqc) ------------------------------ From: Kurt Brorson <[log in to unmask]> Date: Tue, 8 Apr 2014 20:31:39 +0000 To: Kurt Brorson <[log in to unmask]> Subject: Post-doc at CDER/FDA for Chem E graduates Good afternoon, I am taking the liberty of sending an ad for a post-doc position in the bioprocess lab in the Division of Monoclonal Antibodies, CDER/FDA. Could you post it on your departmental bulletin board for graduate students that may looking for a position in the near future? Thank you in advance, Kurt Brorson, Ph.D. Division of Monoclonal Antibodies Office of Biotech Products CDER/FDA Office: Bldg. 64, Rm 1036 Lab: Bldg. 64, Rm. 1029 10903 New Hampshire Ave. Silver Spring MD 20903 Office tel: 301-796-2193 Lab Tel: 301-796-0046 Fax: 301-796-9817 [log in to unmask] ------------------- Research opportunity in Bioprocessing A postdoctoral research fellowship in CDER/FDA’s White Oak Campus is currently available to join a team studying the feasibility of PAT in bioprocessing with the specific aim of better controlling antibody critical quality attributes (CQAs). Conventional biopharmaceutical cell culture involves multiple input factors, such as media type and feed strategy, cell state, and bioreactor engineering settings, all of which can contribute to protein product variability, for example in glycoforms profile. Process Analytical Technology (PAT) is an approach to improving product consistency by introducing real time monitoring and control of product quality. The lab environment has state of the art instrumentation in lab‐scale protein production bioreactor cell culture, preparative scale chromatography and advanced analytical instrumentation. This team‐based project has the potential to lead to improvements in how the stability, potency, safety, and efficacy of biotechnology‐derived biologic drugs are achieved. A Ph.D. degree and experience in biochemistry, microbiology, chemical engineering or molecular biology are required. An excellent record of oral and written English skills is also required. Research experience with bioprocessing, bioreactor cell culture, or chromatographic protein separation is preferred. The position is administered by ORISE. ORISE fellowships are for one year, renewable based on performance. The successful candidate will join a dynamic and highly motivated team of scientists. Salary is commensurate with education and experience. US citizenship, green card, EAD, OPT or CPT is required. An H1 or J1 visa cannot be sponsored for this position. To apply: Please email your CV, a brief description of your research interest, and the contact information for three references to: Kurt Brorson, Ph.D. Division of Monoclonal Antibodies Office of Biotechnology Products Center for Drug Evaluation and Research Food and Drug Administration Bldg 64, Rm 1036 10903 New Hampshire Ave Silver Spring, MD 20903 E‐mail: [log in to unmask] The FDA is an Equal Opportunity Employer.