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We have an exciting opening in our group at Amgen in Digital Integration and Predictive Technologies (DIPT) group in the area of Process Analytics. Job location is Cambridge, MA. For those who are interested please apply (Req #: 34229BR) using the following link or send me an e-mail at [log in to unmask] http://careers.amgen.com/en/jobs/descriptions/sr-engineer-digital- integration-and-predictive-technologies-cambridge-job-5823853 Job Summary: Amgen’s Digital Integration and Predictive Technologies orginization is a global process development function that develops and deploys state of the art advanced computational technologies in: 1) data capture, integration and management, 2) empirical and first principles modeling towards improved process understanding and robustness, and 3) monitoring, prediction and optimization of manufacturing. We are seeking a Senior Engineer to provide hands-on technical support, analyses, and assessments for a broad base of clients globally by leveraging expertise in process analytics, computational and multivariate modeling for production of bio-therapeutics. The Senior Engineer will address a wide variety of challenging problems across many organizations including: drug substance, drug product and drug delivery devices. Responsibilities will include designing and running bench-scale experiments for model- based control studies, preparation of internally reviewed technical reports as well as participation in and presentation of results at department and project meetings. Use of developed models and their underlying technical basis will be deployed and taught to the broader engineering and scientist community responsible for delivering processes to operations Basic Qualifications Doctorate Degree OR Master's Degree & 3 years of Engineering experience OR Bachelor's Degree & 5 years of Engineering experience OR Associate's degree & 10 years of Engineering experience OR High school diploma/GED & 12 years of Engineering experience Preferred Qualifications Ph.D. with experience noted in the basic qualifications above. 5+ years relevant work experience in bio/pharmaceutical applications. Experience in process development and/or Computational Modeling and Control techniques Experience with biopharmaceuticals processes, related unit operations. Solid understanding of biochemical engineering, metabolic flux models and closed-loop control. Hands-on bench or pilot-lab experience to work with experimentalists to generate data for model building and validation Excellent programming skills in any of the following: C++, Perl, Java, C# , Matlab, Python, R Basic understanding of laboratory automation and information systems such as Delta V, OPC and PI. Knowledge of current state of the art technologies and emerging scientific and regulatory directions for process control towards minimizing and controlling process variability as well as new technologies to improve control, information and knowledge management in process lifecycle. Strong interdisciplinary project management skills. Ability to independently uncover and resolve issues associated with the development and implementation of scientific and engineering projects. Should be recognized in the scientific and engineering community through a sustained record of publications and/or patents. Understanding of bulk protein process and formulation/finish unit operations including analytical methods and process controls. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.