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Subject: Chemistry Internship at Portola Pharmaceuticals Description: Portola Pharmaceuticals Inc. is a biopharmaceutical company focused on the development and commercialization of novel therapeutics in the areas of thrombosis, other hematologic disorders and inflammation for patients who currently have limited or no approved treatment options. Portola’s goal is to build an enduring biopharmaceutical company with a foundation of products and product candidates that significantly advance patient care in the areas of thrombosis, other hematologic disorders and inflammation. Portola is headquartered in South San Francisco, California. The summer intern will work with members of the Chemistry Department to assist in understanding the structure-activity relationships of a series of small molecule enzyme inhibitors with the goal of developing novel therapeutics. Using structure-based design strategies, we will optimize chemical leads for their potency, selectivity, and pharmacokinetic profile. The activity of the compounds will be determined using a novel cell based assay. This position includes housing within walking distance of the company. Knowledge, Skills, Abilities and Requirements: -Actively pursuing a Bachelor’s of Science degree -Completed college coursework in biology, chemistry, biochemistry or other related areas -Experience in synthetic chemistry including the synthesis, purification, and characterization of small molecules -An understanding of analytical techniques such as LC-MS and NMR Contact Us: Our company overview and history: http://www.portola.com/Company-Overview Please include a cover letter that highlights your qualifications and matches our requirements and send resumes to [log in to unmask] If you have questions or are interested in applying, we encourage you to contact Cindy Georgette, Staffing Consultant at [log in to unmask] Contact Person: Cindy Georgette Contact Email: [log in to unmask]