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Dear Colleagues, ***** The early registration deadline for FOSBE 2018 is approaching fast and ends on Monday, 06/18/2018. ***** On behalf of the organizing committee, I am pleased to invite you to join us for the 7th International Conference on Foundations of Systems Biology in Engineering (FOSBE 2018), which will take place in Chicago, Illinois, August 5-8, 2018. The field of systems biology has emerged as the bridge between reductionist molecular and cellular biology approaches and the systems-level understanding required to use this knowledge. Drawing upon the revolutionary advances from reductionist approaches in molecular and cellular biology, systems approaches focus on the relationships between the gene, protein, and metabolite responses that compose the individual and population responses at the whole organism level. The primary avenues in this search are (i) defining the causal connections between the plethora of transcriptional, protein, and metabolite players; (ii) linking these microscale networks to system response; and (iii) capturing the dynamics of the system in response to changes at lower scales. The primary objectives of the FOSBE 2018 conference are to provide an in-depth review and critical assessment of the current state-of-the-art, to discuss current and future needs of research, education and training, and to identify new directions, opportunities, and challenges in systems biology. Major conference topics are: • Modeling of Complex Biological Systems • Industrial Applications of Systems and Synthetic Biology • Multi-scale and Multi-omics Experimentation, Data Integration, and Modelling • Network Inference and Modeling • Synthetic Biology • Next Generation Networks and Tools • Systems Biology of Cellular Metabolism • Systems and Synthetic Biology for Biotechnology • Systems Medicine For detailed information about the 7th FOSBE and the program, visit http://www.fosbe.org Best wishes, Juergen Hahn