Dear CAST10 community member, Dr. Jin Wang and I, the Guest Editors of the open access journal Processes (ISSN 2227-9717; indexed in *SCIE* and *Scopus*; http://www.mdpi.com/journal/processes), are inviting you to publish a paper to a Special Issue of Processes: Big Data in Biology, Life Sciences and Healthcare (http://www.mdpi.com/journal/processes/special_issues/big_data_biology) Deadline for submissions: *31 May 2019* *Special Issue Description * Massive quantities of data are being generated in biology, the life sciences and healthcare industries and institutions, which hold the promise of advancing our understandings of various biological systems and diseases, developing new biocatalysts and drugs, as well as delivering more effective patient care and reducing costs, etc. In this Special Issue, we seek research and case studies that demonstrate the application of big data modeling and analysis to support scientific research, drug development, clinical decision making, personalized medicine, and other critical tasks. Example topics include (but are not limited to) the following topics relating big data to biology, the life sciences or healthcare: Novel systems engineering approaches, including modeling and numerical analysis algorithms New statistical tools and algorithms Machine learning and artificial intelligence Integration of systems engineering approaches with machine learning Novel visualization approaches Computer or model-aided diagnostics Model-based drug development Evidence-based medicine Modeling and analysis of data from a multitude of sources Application of wearable devices Public health surveillance *How to Submit* The main types of contributions published in Processes: Articles, Communications, Reviews, Conference Papers, Perspectives, Viewpoints. 1. Instructions for Authors: http://www.mdpi.com/journal/processes/instructions 2. Manuscripts are expected to be submitted through the online system at https://susy.mdpi.com/user/manuscripts/upload/ *About Processes* Processes (ISSN 2227-9717; Impact Factor: 1.279) is a journal published by MDPI AG, Basel, Switzerland. Processes maintains rigorous peer-review and a rapid publication process. *Open Access* (http://www.mdpi.com/about/openaccess): free for readers, with publishing fees paid by authors or their institutions. (http://www.mdpi.com/journal/processes/apc). *High visibility*: indexed by the Science Citation Index Expanded (Web of Science), Scopus and other databases. (http://www.mdpi.com/journal/processes/indexing) *Rapid publication*: Manuscripts are peer-reviewed and a first decision provided to authors approximately 14 days after submission; acceptance to publication is undertaken in 5.98 days (median values for papers published in the first six months of 2018) Please do not hesitate to contact Dr. Jin Wang or myself if you have any question. Sincerely, Peter He, PhD Associate Professor Department of Chemical Engineering Auburn University, AL 36849 334-844-7602 (O) Jin Wang, PhD Walt and Virginia Woltosz Endowed Professor Graduate Program Chair Department of Chemical Engineering Auburn University, AL 36849 334-844-2020 (O)