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*European Symposium on Computer Aided Process Engineering, ESCAPE-31* *June 6-9, 2021, Istanbul, Turkey* *http://escape31.org/ <http://escape31.org/> <http://escape31.org/>* It is our pleasure to welcome you to the 31st International Symposium on Computer Aided Process Engineering (ESCAPE-31) in Istanbul on June 6–9, 2021. The purpose of the meeting is to bring together the community of researchers and practitioners in the area of computer-aided process systems engineering from academia and industry. ESCAPE-31 will focus on the following main themes: Theme 1: Process-product synthesis, design and integration Theme 2. Methods, models and computational tools for PSE Theme 3. Process control and operations Theme 4. CAPE/PSE in energy/water/food nexus and sustainability Theme 5. Process operations and supply chains Theme 6. PSE in biological systems and processes Theme 7. Education in CAPE/PSE & knowledge transfer Accepted papers will be published in Computer Aided Chemical Engineering by Elsevier. The ESCAPE series follows a two-stage evaluation process: the first stage requires abstracts that are limited to a maximum of 3,000 characters including spaces, numbers and punctuation marks, the second stage requires 6-page papers that will be published in Computer Aided Chemical Engineering by Elsevier after acceptance of the paper. The ESCAPE-31 website ( http://escape31.org/) includes abstract and paper submission templates in MS Word and LaTeX. All papers will be reviewed by the Programming Committee and a very limited number of papers will be moved from regular submission to keynote paper. Work presented at the conference will be published (following usual ESCAPE policies) in a new volume of Computer Aided Chemical Engineering book series from Elsevier. Extended papers will be published in a special issue of Computers and Chemical Engineering, *Important Dates* Deadline for abstract submission: *Sep 7, 2020* Notification of abstract acceptance: *Oct 12, 2020* Deadline for paper submission: *Nov 16, 2020* Notification of paper acceptance: *Jan 15, 2021* Deadline for revised paper submission: *Feb 15, 2021* Submission of copyright transfer agreement: *Feb 15, 2021* Looking forward to seeing you in Istanbul. The ESCAPE-31 Organizing Committee -- Metin Turkay Professor of Industrial Engineering, Koc University Rumelifeneri Yolu, Sariyer 34450 Istanbul Tel:+90-212-338-1586; Fax: +90-212-338-1548; http://home.ku.edu.tr/~mturkay/